The TATA box binding protein attaches (binds) to a particular sequence of DNA known as the TATA box. This sequence occurs in a regulatory region of DNA near the beginning of many genes. Once the protein is attached to the TATA box near a gene, it acts as a landmark to indicate where other enzymes should start reading the gene.
Gene expression is highly controlled and regulated in living cells. One of the first steps in gene transcription is
recognition of the promoter site by the TATA box Binding Protein (TBP). TBP recruits other transcriptions factors and
eventually the RNA polymerase II to transcribe the DNA in mRNA.
TATA-binding protein works as part of a larger transcription factor, TFIID, that starts the process of transcription. After it binds to the promoter, it recruits additional transcription factors.