Cannabinoid Receptor

cb1 rc cannabinoid receptor am6538 antagonist anandamide thc seven transmembrane helix  7TMH Rc

Cannabinoid receptor 1 (CB1) complex with THC antagonist AM6538 (spheres model) that inhibit the anandamide (molecule upper-left) bounding. CB1 is a seven trasmembrane receptor and the principal target of delta (9)-tetrahydrocannabinol (THC), a psychoactive chemical from Cannabis sativa with a wide range of therapeutic applications and a long history of recreational use. CB1 is activated by endocannabinoids like anandamide afatty acid neurotransmitter (N-arachidonoylethanolamine or AEA) and is a promising therapeutic target for pain management, inflammation, obesity, and substance abuse disorders.

cb1 rc cannabinoid receptor am6538 agonist anandamide thc seven transmembrane helix 7TMH Rc

Cannabinoid receptor 1 (CB1) complex with delta (9)-tetrahydrocannabinol (THC) (spheres model) that agonizes the anandamide (molecule upper-left) bounding. CB1 is a seven trasmembrane receptor and the principal target of THC, a psychoactive chemical from Cannabis sativa with a wide range of therapeutic applications and a long history of recreational use. CB1 is activated by endocannabinoids like anandamide afatty acid neurotransmitter (N-arachidonoylethanolamine or AEA) and is a promising therapeutic target for pain management, inflammation, obesity, and substance abuse disorders.

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